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Corticosteroids by the body. Prednisone is inactive in the body. Prednisolone prevents the release of substances in the body and, in order to be effective, first must be converted to Prednisolone by enzymes in the liver. Prednisolone is a synthetic corticosteroid which is often simply called steroid, but it should be noted that it is very different from another group of steroids, called anabolic steroids, which have gained notoriety because of their abuse by some athletes and body builders.
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"When the benefits outweigh the potential risk to the fetus. Before using this medication, tell your doctor or pharmacist your medical history, especially of blood flow problem in the brain. Individuals who have developed allergic reactions from aspirin or other NSAIDs may experience an allergic reaction to Celecoxib and should not take Celecoxib."