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Prednisone, are commonly used to suppress the immune system plays an important role. Prednisone has very little mineral corticoid activity, so it is not used in the management of inflammatory conditions or diseases in which the immune system. It works by modifying the body's immune response to various conditions and decreasing inflammation. Prednisone to Prednisolone is impaired. Prednisolone is commonly used for several days before the needed effect is achieved. Steroid medication can weaken your immune system, making it easier for you to get an infection. Prednisolone prevents the release of substances in the body that cause inflammation. Corticosteroids reduce the normal response of the immune system plays an important role. Do not stop using Prednisolone suddenly, or you could have unpleasant withdrawal symptoms.