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Certain types of cancer, including some forms of breast and prostate cancer. What is the most important information I should know about conjugated estrogens? Estrogens increase your risk of developing endometrial hyperplasia, a condition that may lead to cancer of the uterus. What should I discuss with my healthcare provider before taking conjugated estrogens, tell your doctor if you are taking antidepressants or a thyroid medication. Premarin is also controversial because the health risks to women of absorbing a substance made from equine waste may not be fully known. Conjugated estrogens may increase your risk of stroke or blood clots.
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