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Clopidogrel keeps the platelets in your blood from coagulating to prevent unwanted blood clots that can block arteries. Clopidogrel is rapidly absorbed after oral administration of repeated doses of 75 mg Clopidogrel approximately one hour after dosing. Clopidogrel is rapidly absorbed after oral administration of repeated doses of 75 mg Clopidogrel approximately one hour after dosing. Because of this drug action, Clopidogrel can make it easier for you to bleed, even from a minor injury.